Abstract

This study investigated the antioxidant and antimicrobial activity of Eclipta prostrata leaf extract. Fresh and healthy leaves of Eclipta prostrata leaves were collected and extracted using ethanol. Assessment of antioxidant activity of the ethanolic leaf extract was carried out for DPPH radical scavenging activity. Eclipta prostrata showed 77.41% DPPH radical scavenging activity compared to the standard ascorbic acid. Eclipta prostrata leaf extract exhibited antibacterial activity against clinical isolates like Streptococcus pyogens, Staphylococcus aureus, Escherichia coli, Proteus mirabilus and Pseudomonas aeruginosa. The ethanolic leaf extract of Eclipta prostrata can be explored further for its biological activities.

Keywords: Antioxidant, antimicrobial, Eclipta prostrata, radical scavenging, clinical isolates.

Abstract

This study investigated the phytochemical constituents, total flavonoid and phenolic content of Xanthosoma sagittifolium stem extracts. The preliminary phytochemical evaluation showed the presence of glycosides (cardiac glycoside), steroids, flavonoids, tannins, phenols and terpenoids. Chloroform extract showed the presence of majority of phytoconstituents. Methanolic extract contained maximum percentage of phenolic and flavonoid content than aqueous and chloroform extract. Total phenol content in the stem extracts (methanol chloroform and aqueous extract) using the calibration curve was found to be 47.35, 16.35 and 11.8172 mg of Gallic acid equivalents/g dry weight of extract. Total flavonoid content in the stem extracts (methanol chloroform and aqueous extract) using the calibration curve was found to be 119.94, 6.35 and 25.60 mg of quercetin equivalents/g dry weight of the extract. To conclude, methanolic extract showed good amount of phenolic and flavonoid content and hence be explored further for pharmacological properties.

Keywords: Phytochemicals, Xanthosoma sagittifolium, phenols, flavonoids, gallic acid, quercetin.